Proof of Principle Program

This funding stream is intended to allow young investigators and established researchers from other disciplines to enter the field of prion research and supports new approaches into prion research. It will build Alberta's research capacity and ability to address the desired outcomes according to the principles of the Prion Institute.

Proof of Principle (PoP) projects are expected to:

  • Further the objectives of one or more of the theme areas addressing one or more of the desired outcomes of the Prion Institute.
  • Provide an effective entry point into prion-related research and to build Alberta's capacity in relevant areas.
  • Be led by an Alberta- based researcher involving, where appropriate, researchers and facilities elsewhere in Canada and around the globe.
  • Demonstrate that the project is innovative and does not duplicate research being carried out elsewhere nationally or internationally.
  • Support the TSE and Society theme wherever possible.
  • Include a training component for graduate students or post-doctoral fellows that will help build the pool of researchers working on prions and related diseases in Canada.
  • Develop appropriate partnerships and linkages nationally and internationally.

Examples of possible research projects:

  • Training researchers in laboratories with established expertise in innovative prion research
  • Application of novel investigative imaging and diagnostic technologies (for example, nanotechnologies, lab-on-a-chip, biomarkers) to detect TSEs and other diseases with related pathology
  • Developing prototypes for antemortem testing
  • Development of novel risk assessment methodologies

PoP projects should NOT be used:

  • As bridging or emergency funding

  • To support ongoing studies

Eligibility

Researchers must be affiliated with an Alberta post-secondary institution or research organization. The strength of proposals may be enhanced by meaningful collaboration among universities, colleges, industry and policy makers. Applications from individuals or small teams are preferred for Proof of Principle projects.

Budget

Proof of principle projects may be funded up to a maximum level of $100,000 per year, for a maximum of two years. However, funding below this limit may be approved. Budgets for full applications must be carefully documented and clearly justified. Although there is no requirement for matching funds, proof-of-principle projects may be complemented with funds raised from other sources. Prion Institute funds may be used for stipends for trainees, research operating costs, equipment, costs related to national and international collaborations, allowable travel costs, and other reasonable expenditures as required to carry out the project. Project expenses must be consistent with the Tri-Council policy on the use of research grant funding, available at www.nserc.gc.ca.

Application Deadline

There are no Proof of Priniciple Program calls at this time.